Local time:
| Time | Flight | Route | Airline | Aircraft | Status |
|---|---|---|---|---|---|
| Thursday, 24 January | |||||
| 06:00 | NIS132 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 06:20 | TA314 | San Salvador (El Salvador International Airport) | Avianca | AT76 (ATR 72-600) | Scheduled |
| 06:30 | NIS142 | Bluefields (Bluefields) | ATR | Scheduled | |
| 08:00 | NIS110 | Siuna (Siuna) | ATR | Scheduled | |
| 08:00 | NIS1110 | Bonanza (San Pedro) | CNC | Scheduled | |
| 08:02 | AA994 | Miami (Miami International Airport) | American Airlines | B738 (Boeing 737-823) | Scheduled |
| 08:30 | CM163 | San Jose (Juan Santamaria International Airport) | Copa Airlines | 738 | Scheduled |
| 08:56 | CM407 | Guatemala City (La Aurora International Airport) | Copa Airlines | E90 | Scheduled |
| 09:00 | NIS112 | Siuna (Siuna) | ATR | Scheduled | |
| 09:00 | NIS114 | Siuna (Siuna) | ATR | Scheduled | |
| 10:20 | TA396 | Miami (Miami International Airport) | Avianca | E190 (Embraer ERJ-190AR) | Scheduled |
| 10:30 | NIS134 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 11:00 | NIS150 | Bluefields (Bluefields) | ATR | Scheduled | |
| 11:26 | CM827 | Panama City (Tocumen International Airport) | Copa Airlines | 738 | Scheduled |
| 12:00 | NIS124 | San Carlos (San Carlos) | ATR | Scheduled | |
| 12:00 | NIS136 | Waspam (Waspam) | ATR | Scheduled | |
| 12:45 | AM651 | Mexico City (Benito Juarez International Airport) | Aeromexico | E90 | Scheduled |
| 13:43 | AA928 | Miami (Miami International Airport) | American Airlines | B738 (Boeing 737-823) | Scheduled |
| 14:00 | NIS138 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 14:30 | NIS148 | Bluefields (Bluefields) | ATR | Scheduled | |
| 15:20 | AA2592 | Miami (Miami International Airport) | American Airlines | B738 (Boeing 737-823) | Scheduled |
| 17:10 | CM105 | Panama City (Tocumen International Airport) | Copa Airlines | 738 | Scheduled |
| 17:30 | TA397 | San Salvador (El Salvador International Airport) | Avianca | E190 (Embraer ERJ-190AR) | Scheduled |
| Friday, 25 January | |||||
| 06:00 | NIS132 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 06:20 | TA314 | San Salvador (El Salvador International Airport) | Avianca | E190 (Embraer ERJ-190AR) | Scheduled |
| 06:30 | NIS142 | Bluefields (Bluefields) | ATR | Scheduled | |
| 08:00 | NIS110 | Siuna (Siuna) | ATR | Scheduled | |
| 08:00 | NIS1110 | Bonanza (San Pedro) | CNC | Scheduled | |
| 08:02 | AA994 | Miami (Miami International Airport) | American Airlines | B738 (Boeing 737-823) | Scheduled |
| 08:30 | CM163 | San Jose (Juan Santamaria International Airport) | Copa Airlines | 738 | Scheduled |
| 08:56 | CM407 | Guatemala City (La Aurora International Airport) | Copa Airlines | E90 | Scheduled |
| 09:00 | NIS114 | Siuna (Siuna) | ATR | Scheduled | |
| 09:00 | NIS112 | Siuna (Siuna) | ATR | Scheduled | |