Local time:
| Time | Flight | Route | Airline | Aircraft | Status |
|---|---|---|---|---|---|
| Friday, 3 April | |||||
| 07:33 | CM169 | San Jose (Juan Santamaria International Airport) | Copa Airlines | 73G | Scheduled |
| 08:07 | CM405 | Guatemala City (La Aurora International Airport) | Copa Airlines | 738 | Scheduled |
| 09:10 | NIS133 | Puerto Cabezas (Puerto Cabezas) | La Costena | AT4 | Scheduled |
| 09:30 | NIS143 | Bluefields (Bluefields) | La Costena | AT4 | Scheduled |
| 10:40 | NIS111 | Siuna (Siuna) | La Costena | ATR | Scheduled |
| 11:00 | AG930 | Havana (Jose Marti International Airport) | Aruba Airlines | 320 | Scheduled |
| 11:30 | NIS111 | Bonanza (San Pedro) | La Costena | AT4 | Scheduled |
| 11:30 | NIS1111 | Siuna (Siuna) | La Costena | AT4 | Scheduled |
| 11:40 | NIS113 | Siuna (Siuna) | La Costena | ATR | Scheduled |
| 11:40 | AA2243 | Miami (Miami International Airport) | American Airlines | Canceled | |
| 12:30 | CM106 | Panama City (Tocumen International Airport) | Copa Airlines | 738 | Scheduled |
| 13:00 | NIS135 | Puerto Cabezas (Puerto Cabezas) | La Costena | AT4 | Scheduled |
| 15:10 | NIS137 | Waspam (Waspam) | La Costena | ATR | Scheduled |
| 16:18 | CM826 | Panama City (Tocumen International Airport) | Copa Airlines | E90 | Scheduled |
| 17:00 | NIS149 | Bluefields (Bluefields) | La Costena | AT4 | Scheduled |
| 17:10 | NIS139 | Puerto Cabezas (Puerto Cabezas) | La Costena | AT4 | Scheduled |
| 17:35 | NIS508 | Tegucigalpa (Toncontin Airport) | La Costena | AT4 | Scheduled |
| 19:38 | AA993 | Miami (Miami International Airport) | American Airlines | Scheduled | |
| 22:00 | CM712 | Panama City (Tocumen International Airport) | Copa Airlines | E90 | Scheduled |
| Saturday, 4 April | |||||
| 07:33 | CM169 | San Jose (Juan Santamaria International Airport) | Copa Airlines | 73G | Scheduled |
| 08:07 | CM405 | Guatemala City (La Aurora International Airport) | Copa Airlines | 738 | Scheduled |
| 08:30 | AG930 | Havana (Jose Marti International Airport) | Aruba Airlines | 320 | Scheduled |
| 09:10 | NIS133 | Puerto Cabezas (Puerto Cabezas) | La Costena | AT4 | Scheduled |
| 09:30 | NIS143 | Bluefields (Bluefields) | La Costena | AT4 | Scheduled |
| 10:40 | NIS111 | Siuna (Siuna) | La Costena | ATR | Scheduled |
| 11:30 | NIS111 | Bonanza (San Pedro) | La Costena | AT4 | Scheduled |
| 11:30 | NIS1111 | Siuna (Siuna) | La Costena | AT4 | Scheduled |
| 11:40 | NIS113 | Siuna (Siuna) | La Costena | ATR | Scheduled |
| 11:40 | AA2243 | Miami (Miami International Airport) | American Airlines | Canceled | |
| 11:57 | AM650 | Mexico City (Benito Juarez International Airport) | Aeromexico | E90 | Scheduled |
| 12:30 | CM106 | Panama City (Tocumen International Airport) | Copa Airlines | E90 | Scheduled |
| 12:45 | DL369 | Atlanta (Hartsfield-Jackson Atlanta International Airport) | Delta Air Lines | 73W | Scheduled |
| 13:00 | NIS135 | Puerto Cabezas (Puerto Cabezas) | La Costena | AT4 | Scheduled |
| 14:00 | M6761 | San Salvador (El Salvador International Airport) | Amerijet International | 76F | Scheduled |
| 15:10 | NIS137 | Waspam (Waspam) | La Costena | AT4 | Scheduled |