Local time:
| Time | Flight | Route | Airline | Aircraft | Status |
|---|---|---|---|---|---|
| Monday, 18 February | |||||
| 01:23 | M6859 | Miami (Miami International Airport) | Amerijet International | 762 | Scheduled |
| 07:35 | CM169 | San Jose (Juan Santamaria International Airport) | Copa Airlines | 738 | Scheduled |
| 08:07 | CM405 | Guatemala City (La Aurora International Airport) | Copa Airlines | E90 | Scheduled |
| 09:10 | NIS133 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 09:30 | NIS143 | Bluefields (Bluefields) | ATR | Scheduled | |
| 09:35 | NIS508 | Tegucigalpa (Toncontin Airport) | ATR | Scheduled | |
| 09:35 | TA396 | San Salvador (El Salvador International Airport) | Avianca | E190 (Embraer ERJ-190AR) | Scheduled |
| 10:35 | 5X378 | Miami (Miami International Airport) | UPS Airlines | 763 | Scheduled |
| 10:40 | NIS111 | Siuna (Siuna) | ATR | Scheduled | |
| 11:30 | NIS1111 | Bonanza (San Pedro) | CNC | Scheduled | |
| 11:40 | NIS113 | Siuna (Siuna) | ATR | Scheduled | |
| 11:40 | NIS115 | Siuna (Siuna) | ATR | Scheduled | |
| 12:28 | CM106 | Panama City (Tocumen International Airport) | Copa Airlines | E90 | Scheduled |
| 12:31 | NK499 | Fort Lauderdale (Fort Lauderdale-Hollywood International Airport) | Spirit Airlines | A321 (Airbus A321-231) | Scheduled |
| 12:42 | AA2243 | Miami (Miami International Airport) | American Airlines | B738 (Boeing 737-823) | Scheduled |
| 13:00 | UA1432 | Houston (George Bush Intercontinental Airport) | United Airlines | B737 (Boeing 737-724) | Scheduled |
| 13:00 | NIS135 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 14:05 | NIS151 | Bluefields (Bluefields) | ATR | Scheduled | |
| 14:10 | NIS147 | Bluefields (Bluefields) | ATR | Scheduled | |
| 14:18 | AA1429 | Miami (Miami International Airport) | American Airlines | B738 (Boeing 737-823) | Scheduled |
| 16:10 | CM826 | Panama City (Tocumen International Airport) | Copa Airlines | 738 | Scheduled |
| 16:45 | TA397 | Miami (Miami International Airport) | Avianca | E190 (Embraer ERJ-190AR) | Scheduled |
| 17:10 | NIS139 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 17:30 | NIS149 | Bluefields (Bluefields) | ATR | Scheduled | |
| 19:14 | CM712 | Panama City (Tocumen International Airport) | Copa Airlines | 738 | Scheduled |
| 19:49 | AA993 | Miami (Miami International Airport) | American Airlines | B738 (Boeing 737-823) | Scheduled |
| 21:20 | TA315 | San Salvador (El Salvador International Airport) | Avianca | A20N (Airbus A320-251N) | Scheduled |
| Tuesday, 19 February | |||||
| 07:35 | CM169 | San Jose (Juan Santamaria International Airport) | Copa Airlines | 738 | Scheduled |
| 09:10 | NIS133 | Puerto Cabezas (Puerto Cabezas) | ATR | Scheduled | |
| 09:30 | NIS143 | Bluefields (Bluefields) | ATR | Scheduled | |
| 09:35 | TA396 | San Salvador (El Salvador International Airport) | Avianca | E190 (Embraer ERJ-190AR) | Scheduled |
| 10:40 | NIS111 | Siuna (Siuna) | ATR | Scheduled | |
| 11:30 | NIS1111 | Bonanza (San Pedro) | CNC | Scheduled | |
| 11:35 | AM650 | Mexico City (Benito Juarez International Airport) | Aeromexico | E90 | Scheduled |
| 11:40 | NIS113 | Siuna (Siuna) | ATR | Scheduled | |
| 11:40 | NIS115 | Siuna (Siuna) | ATR | Scheduled | |